A LITTLE boy begins to lose his teeth, before doctors tell his shocked mother he has an extremely rare disease.
Myles Tucker, three, is one of only 120 children in the world battling the condition.
He is currently living with 4H leukemia, after his family noticed he was missing teeth.
His genetic condition is only the third to be diagnosed in Wales, where the family comes from.
The boy’s mother, Georgia Hughes, said she took her boy to the doctor after noticing a change in his mouth.
She told North Wales Live: “I talked about this with his pediatrician and she referred us to Alder Hey and it was there that he was diagnosed with hypodontia – collectively part of the leukemic dystrophy. .
“Myles is a beautiful and sweet boy. He absolutely loves preschool and this condition doesn’t stop him.
“He was full of determination and always had a smile on his face.
“The overall life expectancy of a child with leukemia is 10 years. He will need more professional care and support as he gets older.
“As the disease progresses, we need to watch out for things like difficulty swallowing. These are things that haven’t happened yet, but we’ve been told they can happen.
“I hope that by making more people aware of this condition, we can help others understand it and know what to look out for.”
The condition is difficult to detect, but there are a number of signs that can indicate if a child has it.
Abnormal growth of teeth, or lack of them, is one.
Another symptom is delayed puberty, but this appears much later in childhood.
It can be detected through MRI scans, clocking if there is a presence of muscle insufficiency (an underdeveloped “cortex”).
Myles’ condition was diagnosed after he had two scans to confirm that he had hypoplasia.
The disease is caused by an abnormal accumulation of substances called sulphatides in nerve cells, especially in the white matter of the brain.
It replaces myelin, which is necessary for the normal transmission of messages between nerves.
With MLD, the substance cannot be eliminated from the body in the normal process, so messages to other parts are blocked and do not work.
Georgia has established a fundraising page hope to help fund the discovery of a cure.
She wrote: “4H syndrome dramatically shortens your lifespan and has serious effects.
“As much as I want to raise awareness as much as I can, I certainly hope to be able to cure all of our children.”
https://www.the-sun.com/health/4262817/boy-losing-teeth-rare-illness/ My boy started to lose his teeth